Poor lifestyles may trigger a key gene mutation linked to worse prognosis [for breast cancer], the British Journal of Cancer reports.
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"Deprivation alone doesn't cause breast cancer, but can affect prognosis when p53 is damaged as a result of lifestyle choices commonly associated with deprivation." Dr Lee Baker, Dundee University
Normally, the p53 gene is a "tumour suppressor", telling cells with cancerous or pre-cancerous changes to self-destruct before they can thrive.
However, when it mutates, that ability is reduced or removed, making the appearance of cancer far more likely.
- 3 votes
Wow! That is a huge discovery. Thanks for the article, Loretta!
Think of the progress that can be made in avoiding or curing cancer if they use this to develop strategies to help poor women (and all women, for that matter) to eat better.
- 3 votes
Now I know that it doesn't just seem like the odds of having cancer stacked against poorer women, it's been proven. Maybe I can dream a little and hope that this provides some momentum for health care reform!
- 1 vote
The researchers looked at frozen tumour tissue samples from a total of 246 women who underwent cancer treatment between 1997 and 2001.
So, this is how or what P53 does fine. But claiming a scientific breakthrough that was reduced to the way women lived could have a direct bearing on their P53 gene sounded of marketing for cancer research funding. Studies show that while Hispanic/ Latina women have lower breast cancer rates, they are more likely to die from the cancer. Because of language and income barriers, lack of health insurance, and low awareness of breast cancer risks and screening methods, Hispanic/ Latina women are often diagnosed during the late stages of breast cancer. But they still have lower breast cancer rates. Cancer in 246 women cannot determine such bold claims in my view.
- 1 vote
In the world of research, studies always begin small. That all they can get funding for. Once the first study is done, they can go back and try to get more funding based on their results.
Having studies in any field or thesis start small saves on funding. It helps weed out the studies that don't pan out with meaningful results and leaves more funds for those that do.
I'm sure this won't be the last bit of research on this.
- 2 votes
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